health

A year and some months ago, when the whole COVID-19 thing was just getting out of second gear, one of the doctors I see recommended that Carol and I take zinc and the OTC supplement quercetin every day. The explanation was simple: Quercetin is a zinc ionophore. Ionophores are chemicals able to transport certain ions through cell membranes through which those ions would not ordinarily pass. Zinc is known to attack viruses of all sorts, especially cold and flu viruses. Quercetin attaches to zinc ions and escorts them through cell membranes, into the cells where viruses replicate. Zinc stops virus replication cold.

This sounded familiar, and it was. About that time I had begun hearing of the work of Dr. Zev Zelenko, a New York physician who had begun treating early COVID-19 patients with a drug cocktail consisting of hydroxychloroquine (HCQ), Zinc, and an antibiotic. Dr. Zelenko has a wonderful metaphor describing the cocktail’s operation: Zinc is the bullet. HCQ is the gun. Sure, it’s a little more complex than that, but despite metric megatonnes of anti-HCQ bullshit in the media, the cocktail works.

I’ve seen quercetin described as a zinc ionophore in many places. HCQ is also a known zinc ionophore. It’s a prescription drug that must be taken under medical supervision to avoid certain side effects. However, people I know personally are taking it every day and have for years for autoiummune disorders. I’m not sure how you measure the effectiveness of one zinc ionophore vs. another, so it’s unclear how “strong” an ionophore has to be. Everything I’ve read suggests that quercetin is strong enough to kill viruses wholesale by escorting zinc into cells.

Quercetin has, at best, mild side effects. It’s found in many foods, including kale. Alas, I won’t eat kale, so I take it as an extract in a gelcap. Carol and I followed the physician’s advice, and we’ve been taking 800 mg of quercetin once daily in a formula that includes bromelain. We also take 50 mg zinc daily in the form of zinc gluconate. I’ve talked about this before here on Contra, though it may have been a whole year ago or more. I bring it up again because Carol and I have noticed something unrelated to COVID-19: Neither of us has gotten a cold since we began taking quercetin plus zinc.

And that, my friends, is worth something. My long-time readers have heard me bitch about catching colds and feeling miserable down the years. I get one or sometimes two bad colds a year, and a scattering of sniffles that last for a few days and vanish. We get flu shots, but we still got the flu really bad back at the end of 2017. So the experiment is this: Even though we’re fully vaccinated, we’re going to keep taking quercetin plus zinc, and see how long it is before either of us catches a cold or flu. (We’ll still get our flu shots. I’m a strong believer in vaccination.)

Now, a lot of the country is still hiding out, though here in Arizona mask mandates are mostly a thing of the past. So it’s possible that we ducked colds for the past fourteen months by simply not rubbing shoulders with people much. Those days are past. We shop at big stores like Safeway and Target and Costco even when they’re crowded and nobody has masks. In other words, we’re more or less back to normal life. And my experience of “normal life” prior to COVID was (at least) one cold a year.

Carol and I aren’t worried about COVID anymore. Is it possible that we don’t have to worry about catching colds either? I’m turning 69 in a week. I’ll recap in another year. There’s still no cure for the common cold, but if two OTC supplements can stop colds before they start, man, I call that a revolution–and one helluva birthday present!

I’ve been scratching my head a lot lately, and I need to stop before I wear through my scalp. (My natural armor has been mostly gone for thirty-five years.) It’s a natural, nay obvious question, which I’m putting in bold and giving its own paragraph:

If masks prevent SARS-CoV-2 infections, where did the current explosion of cases and deaths come from?

Take a look at the screenshot below. This is from the Arizona Department of Health Services’ COVID-19 dashboard. The graph is deaths by date of death for the entire state of Arizona. The curve starts heading toward the sky during the last week in October.

Maricopa County, where we live, issued a mask mandate on June 19, 2020. That was right about when the first near-vertical slope in the graph began. It took a few weeks for the mandate to catch on, but by August 1, it was pretty much universal. That’s about when the curve started to fall. There was a certain amount of crowing that the mask mandate had brought the pandemic under control in the state.

Then the end of October happened.

Now, I’ve been watching not only whether people are wearing masks in retail outlets and offices (they are) but also what kinds of masks and how they’re being worn. Over time, the masks are getting better. I’m actually seeing KN95 masks with some frequency, and it’s been a couple of weeks since I’ve seen a useless “train robber” bandana mask anywhere. Mask adherence in the state is at 90%, which aligns with what I’ve seen, if perhaps on the low side. That’s a mighty high rate.

So again, my question: With mask adherence at 90%, why is the curve still so high? Note that the graph is of the days deaths happen, not when they are reported. Death reports are not all received by the state on the days deaths happen, and reports from rural areas can take a week or more to get to AzDHS. What looks like a falling curve at the right edge of the graph may simply be due to lag time in reporting.

There is certainly some inflation of death counts due to the problem of “with COVID but not of COVID.” Some. I don’t think that kind of confusion can cause the numbers we’re seeing here. And it’s inevitable that a certain amount of fraud happens; I’ve seen the news stories describing gunshot suicides, car accidents, and victims of alcohol poisoning described as COVID-19 deaths–some without a positive test for the virus. However, if there had been enough fraud to cause this explosion in deaths, somebody somewhere would have said something.

Wouldn’t they?

Ok. Although I’m open to other theories, I think it’s significant that something happened in the last week of October: Arizona temperatures crashed hard. We had a long, lingering summer here. Mid-October was still giving us 90+ degree days. That went down into the 60s and 70s in a big hurry.

It’s long been known that viral respiratory diseases become much more prevalent in cold weather. Why this should happen isn’t known with certainty. One theory is that influenza and corona viruses have a coating that becomes more rugged in colder temps, giving the virus a longer survival time in air and even in sun. Dry weather favors viruses for reasons that, again, are far from clear.

Well, in Arizona we have dry weather in spades, year-round. Cold, not so much. In fact, a typical winter’s day here is probably about the same temp as a typical summer’s day in North Dakota. Given the uncertainty about what causes viruses to infect more readily in winter, could it be a conjunction of cooler (than usual) temps and extreme dryness? Or (and I like this one better) is there something about the effect of a fall in temperatures (the delta, not the absolute temps) on the human body that gives the virus free rein?

That’s the only theory I have that I haven’t already shot down. It wasn’t Thanksgiving gatherings; the curve took off close to a month before Thanksgiving. And for all that, I consider it pretty thin gruel. It’s dry here probably 340 days a year. It’s even drier in summer than winter.

The theory that people spend more time indoors than outdoors in winter doesn’t apply in Arizona. The reverse is largely the case: When it’s 110 degrees outside, most people stay indoors, or maybe stand up to their necks in the pool. Winter is when people jog, bike, hike, and work outdoors, getting lots of fresh air and plenty of sun (and thus crucial Vitamin D) on their faces, arms, and legs.

Again, where the hell did that near-vertical runup in deaths come from?

I’ll tell you where it didn’t come from: People ditching their masks. The fact that mask compliance is at 90+% during an explosion in COVID-19 deaths screams out something a lot of people don’t want to hear: Masks don’t prevent infection. If they did, the increase would have been a lot more gradual, and probably a lot lower in magnitude.

Let me put it in short, simple words: Masks have been sold as a means of stopping the spread of SARS-CoV-2. They’ve been sold hard. Mask skeptics get called a whole lot of dirty words, even though we wear masks as a courtesy to the rule of law. Faced with a graph like the one the State of Arizona itself puts out, what are we supposed to think?

The graph says something else, perhaps a little more quietly: There are no COVID-19 experts. We still have very little understanding of how this thing spreads and (especially) why it hits some people so devastatingly hard, and others barely at all. When our (often self-appointed) experts told us to put on masks, we put on masks. And then the graph went through the roof.

I wish I had answers. I don’t. Why two peaks instead of one? What had been going on between the end of July and the end of September? Were we doing something right? If so, what? And what did we start doing wrong in late October?

Nobody knows. Read that again: Nobody knows.

If I figure it out, you’ll read about it here.